NCT02423070


Genome Research Alliance for Transplantation (GRAfT)



Adult


This study seeks to evaluate the relationship between donor-derived cell-free DNA and transplant rejection in heart and lung transplant patients. (Advanced Heart Failure group offers this study for heart transplant patients only.)

This is a mid-Atlantic, multicenter prospective study to assess utility of donor-derived cell-free DNA as a marker of allograft rejection, cardiac allograft vasculopathy, CMV infection and other post-transplant complications.


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15-2168


Cardiovascular Precision Medicine Study



Adult


The field of Cardiology has made tremendous strides to reduce cardiovascular (CV) disease over the past several decades through reduction of risk factors and novel medical treatment to manage disease once present. However, much work is still needed to combat CVD. At the Inova Heart and Vascular Institute we are collecting biological samples from patients undergoing cardiac catheterization for genomic, biochemical, molecular and cellular analyses. It is hoped that future analyses on these samples will help us learn what factors predispose patients to develop cardiovascular disease, cause progression of symptoms and/or predict response to various therapies. Our ultimate goal is to be able to predict long-term clinical outcomes in patients who are living with cardiovascular disease to further reduce the incidence, morbidity and mortality rates of CVD.

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